Naranjan S. Dhalla,Peter Zahradka,Ian M.C. Dixon,Robert E.'s Angiotensin II Receptor Blockade: (Progress in Experimental PDF

By Naranjan S. Dhalla,Peter Zahradka,Ian M.C. Dixon,Robert E. Beamish

the connection among angiotensin II and high blood pressure was once confirmed in 1898 while angiotensin II used to be proven to modulate systemic blood strain. Over the intervening a long time, an entire characterization of the renin-angiotensin method (RAS) has been completed, and our realizing of its biochemistry and body structure has ended in the directed improvement of brokers such ·as ACE inhibitors and receptor antagonists able to controlling high blood pressure. extra lately, it was once proven that angiotensin II is secreted inside of sure tissues and that those tissue-specific platforms function independently of the systemic RAS. the radical idea that angiotensin II regulates a few cardiovascular approaches which are unrelated to blood strain has renewed the curiosity of either uncomplicated and medical scientists in angiotensin II. The organization among angiotensin II and cardiac progress, particularly, has indicated that cures at the moment in use for high blood pressure could have direct software to the remedy of center failure. The Manitoba Cardiovascular discussion board on Angiotensin Receptor Blockade in Winnipeg was once convened October 18-20, 1996 to envision the medical and easy points of angiotensin receptor biology as they follow to high blood pressure and middle failure. additionally, the capability therapy of those stipulations utilizing particular angio­ tensin receptor antagonists used to be addressed in the context in their rapid healing program and destiny potential.

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Angiotensin II Receptor Blockade: (Progress in Experimental Cardiology) by Naranjan S. Dhalla,Peter Zahradka,Ian M.C. Dixon,Robert E. Beamish

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